Dr. Grishchuk’s research is focused on therapy-oriented approach to rare neurologic disorders. She received her PhD from the Engelhardt Institute of Molecular Biology in Russia where she was trained as a molecular and cell biologist and began to work in the field of rare diseases. Her interest in neurodegenerative disorders bloomed during her postdoctoral training at the Brain Mind Institute, EPFL, and the University of Lausanne in Switzerland. Working to elucidate the role of lysosome in brain damage and dysfunction she developed strong interest in translational research bringing scientific discoveries from the lab bench to the bedside. Dr. Grishchuk joined Mass General as a postdoctoral fellow in 2010 under the mentorship of Susan A. Slaugenhaupt, PhD to work on a lysosomal disease mucolipidosis IV. Presently, the efforts of her laboratory are focused on preclinical development AAV gene therapies for lysosomal and autophagic CNS disorders.