Artificial Intelligence
April 23–25, 2018
Boston, MA • United States

First Look

2017: The Next Wave of Cardiovascular Breakthroughs

First Look

Early career Harvard Medical School investigators kicked-off the 2017 World Medical Innovation Forum with rapid fire presentations of their high potential new technologies. Nineteen rising stars from Brigham Health and Massachusetts General Hospital gave ten-minute presentations and highlighted their discoveries and insights that will be the disruptive cardiovascular care of the future. This session is designed for investors, leaders, donors, entrepreneurs and investigators and others who share a passion for identifying emerging high-impact technologies. The top presenter each from BWH and MGH was awarded the Austen-Braunwald Innovation Prize on Day 2 of the Forum. The prize carries a $10,000 award.

2017 World Forum First Look Book | Cardiovascular

Novel Target Discovery Pipeline for Calcific Aortic Valve Disease
Elena Aikawa, MD, PhD
Director, Heart Valve Translational Research Program, Brigham and Women's Hospital; Associate Professor of Medicine, Harvard Medical School

A zebrafish pipeline for cardiovascular precision medicine
Manu Beerens, PhD
Postdoctoral Research Fellow, Brigham and Women's Hospital; Harvard Medical School

Using zebrafish to understand and harness cardiac regeneration
Caroline Burns, PhD
Associate Biologist, Massachusetts General Hospital; Associate Professor of Medicine, Harvard Medical School

Bioactive Lipid Profiling Can Identify Potential Targets for Altering Life Course Trajectories Toward Cardiometabolic Disease
Susan Cheng, MD
Associate Physician, Brigham and Women's Hospital, Partners HealthCare; Assistant Professor, Harvard Medical School

Small Molecule Predictors of Outcome After Cardiac Interventions
Sammy Elmariah, MD
Assistant in Medicine, Massachusetts General Hospital; Assistant Professor of Medicine, Harvard Medical School

Translational trials in microRNAs
Mark Feinberg, MD
Physician, Brigham and Women's Hospital; Associate Professor of Medicine, Harvard Medical School

New approaches to controlling stem cell fate
Yick Fong, PhD
Research Scientist, Brigham and Women's Hospital; Assistant Professor of Medicine, Harvard Medical School

Exercise Prescription to Improve Cardiovascular and Cancer Outcomes in Cancer Survivors
John Groarke, MD
Cardiologist, Brigham and Women's Hospital; Instructor of Medicine, Harvard Medical

Personalizing Diabetic Management with Hemoglobin A1c
John Higgins, MD
Associate Pathologist, Massachusetts General Hospital; Associate Professor, Harvard Medical School

Characterizing an Early HFpEF Phenotype: Cardiometabolic Disease and Pulmonary Hypertension
Jennifer Ho, MD
Assistant Physician, Massachusetts General Hospital; Member of the Faculty of Medicine, Harvard Medical School

Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease
Amit Khera, MD
Cardiologist, Massachusetts General Hospital; Instructor, Harvard Medical School

A Novel Epigenetic Complex Implicated in Thoracic Aortic Aneurysm (TAA)
Mark Lindsay, MD, PhD
Physician, Massachusetts General Hospital; Assistant Professor, Harvard Medical School

Atrial Fibrillation: Genetic Basis and Clinical Implications
WINNER: Steven Lubitz, MD
Cardiac Electrophysiologist, Massachusetts General Hospital

Targeting Vascular Calcification to Prevent Cardiovascular Disease
Rajeev Malhotra, MD
Staff Cardiologist, Associate Medical Director of the Cardiac Intensive Care Unit, Associate Director of the Cardiopulmonary Exercise Laboratory, Massachusetts General Hospital; Instructor in Medicine, Harvard Medical School

Stratifying Exercise Dysfunction
Bradley Maron, MD
Association Physician, Brigham and Women's Hospital; Assistant Professor, Harvard Medical School

Novel Mouse Models of Remote Cardioprotection
WINNER: Benjamin Olenchock, MD, PhD
Cardiovascular Medicine Specialist, Brigham and Women's Hospital; Instructor in Medicine, Harvard Medical School

Harnessing Endogenous Mechanisms of Programmed Gene Expression for Therapeutic Benefit In Cardiometabolic Disorders
Jorge Plutzky, MD
Director, Preventive Cardiology, Cardiovascular Medicine, Brigham and Women's Hospital

Aging and the activin type II receptor pathway: a new target for heart failure therapy?
Jason Roh, MD
Assistant in Medicine, Massachusetts General Hospital; Instructor, Harvard Medical School

Signaling and pulmonary vascular disease
Paul Yu, MD, PhD
Physician, Brigham and Women's Hospital; Associate Professor of Medicine, Harvard Medical School