Past Forum: 2017
Boston
Summary
Cardiovascular and cardiometabolic care are among the core drivers of the current healthcare revolution. With 24 million heart disease-related deaths forecasted for 2030, current legacy delivery systems are undergoing disruption by a convergence of new therapies, new technologies, digital integration and the engagement of completely new industries to move patients to improved health and sustained well-being.
At more than $200 billion annually, cardiovascular remains health care’s largest market. It is dominated by drugs for the treatment of hypertension, hyperlipidemia, thrombosis, and cardiomyopathy, as well as devices for coronary and peripheral vascular interventions, rhythm management, and valve repair. The Forum was based around how these traditional fields are being transformed by innovative approaches combining new therapies, ‘omics, digital diagnostics, education and engagement with new delivery platforms to significantly enhance the lives of millions of patients worldwide.
Keynoters
Stéphane Bancel
- CEO, Moderna
George Barrett
- CEO, Cardinal Health
Robert Bradway
- CEO, Amgen
Nancy Brown
- CEO, American Heart Association
Robert Califf, MD
- Commissioner of Food and Drugs, US Food and Drug Administration
Tony Coles, MD
- CEO, Yumanity Therapeutics
Timothy Ferris, MD
- CEO, MGPO
- Professor of Medicine, HMS
John Flannery
- CEO, GE Healthcare
Paul Fonteyne
- CEO, Boehringer Ingelheim USA
Jean-François Formela, MD
- Partner, Atlas Venture
Gary Gibbons, MD
- Directory, NHLBI
Ludovic Helfgott
- Global VP, Cardiovascular, Renal and Metabolism, AstraZeneca
Omar Ishark, PhD
- CEO, Medtronic
Michael Jaff, DO
- President, NWH
- Professor of Medicine, HMS
Paul LaViolette
- Managing Partner and COO, SV Life Sciences Advisers
John Lechleiter, PhD
- Chairman, Eli Lilly and Company
Joseph Loscalzo, MD, PhD
- Chairman, Department of Medicine, Physician-in-Chief, BWH
- Hersey Professor of the Theory and Practice of Medicine, HMS
- Soma Weiss, MD Distinguished Chair in Medicine, HMS
Mike Mahoney
- CEO, Boston Scientific
Jessica Mega, MD
- CMO, Verily
Michael Minogue
- CEO, Abiomed
Jeff Mirviss
- SVP and President, Peripheral Interventions, Boston Scientific
Michael Mussallem
- CEO, Edwards Lifesciences
Betsy Nabel, MD
- President, Brigham Health
- Professor of Medicine, HMS
Peter Orszag, PhD
- Vice Chairman, Corporate and Investment Banking, Citigroup
Ora Pescovitz, MD
- SVP and US Medical Leader, Eli Lilly and Company
Jonathan Rennert
- CEO, ZOLL Medical
Marc Semigran, MD
- CMO, MyoKardia
Tamara Syrek Jensen, Director, Coverage and Analysis Group
- CMS,
Frans Van Houten
- CEO, Philips
Panels
Day One: Monday, May 1, 2017
First Look: The Next Wave of Cardiology Breakthroughs
Discovery Café Breakout Sessions: Sharing Perspectives
Opening Remarks
- Introducer: Anne Klibanski, MD, Chief Academic Officer, Partners HealthCare; Laurie Carrol Guthart Professor of Medicine, Academic Dean for Partners, Harvard Medical School
- David Torchiana, MD, CEO, Partners HealthCare
Reinventing Cardiac Care
- Calum MacRae, MD, PhD, Chief of Cardiovascular Medicine, BWH; Associate Professor of Medicine,Harvard Medical School
- Anthony Rosenzweig, MD, Chief, Cardiology Division, MGH; Professor of Medicine, Harvard Medical School
CEO Roundtable: Today’s Learning, Tomorrow’s Opportunities
- Moderator: Benjamin Pless, Executive in Residence, Partners HealthCare Innovation
- John Flannery, CEO, GE Healthcare
- Michael Minogue, CEO, Abiomed
- Michael Mussallem, CEO, Edwards Lifesciences
- Timothy Ring, CEO, Bard
- Lewis Sandy, MD, EVP, Clinical Advancement, UnitedHealth Group
Tackling the AFib Epidemic
- Moderator: Jagmeet Singh, MD, DPhil, Associate Chief, Cardiology Division, MGH Heart Center; Professor of Medicine, Harvard Medical School
- Patrick Ellinor, MD, PhD, Director, Cardiac Arrhythmia Service, MGH; Associate Professor, Harvard Medical School
- Colleen Fowler, VP, GM, AF Solutions, Medtronic
- Parashar Patel, VP, Global Health Policy, Boston Scientific
- Michael Rousseau, President, Cardiovascular and Neuromodulation, Abbott
- Steven Zelenkofske, DO, VP US Medical Affairs, CVMD TA, AstraZeneca
1:1 Fireside Chat: Omar Ishrak, PhD, CEO, Medtronic
- Moderator: Paul LaViolette, Managing Partner & COO, SV Life Sciences Advisers
- Omar Ishrak, PhD, CEO, Medtronic
Heart Failure’s Therapeutic Mandate
- Moderator: Akshay Desai, MD, Director, Heart Failure Disease Management, BWH; Associate Professor, Harvard Medical School
- Philip Adamson, MD, VP and Medical Director, Abbott
- Craig Basson, MD, PhD, VP, Global Translational Medicine Head (CVM), Novartis Institutes for BioMedical Research; Senior Lecturer, Harvard Medical School
- Marc Semigran, MD, CMO, Myokardia
- Kenneth Stein, MD SVP, CMO, Global Health Policy, Rhythm Management, Boston Scientific
CLINICAL HIGHLIGHT: A New Chapter of PAD
- Moderator: Michael Jaff, DO, President, Newton-Wellesley Hospital, Partners HealthCare; Professor of Medicine, Harvard Medical School
- Douglas Drachman, MD, Director, Cardiology and Interventional Cardiology Fellowship Programs, MGH; Assistant Professor of Medicine, Harvard Medical School
- Tamara Syrek Jensen, Director, Coverage and Analysis Group, CMS
- Misti Malone, PhD, Chief, Peripheral Interventional Devices Branch, Food and Drug Administration
- Shaden Marzouk, MD, CMO, Cardinal Health
- Matthew Menard, MD, Co-Director, Endovascular Surgery, BWH; Assistant Professor, Harvard Medical School
- Jeff Mirviss, SVP and President, Peripheral Interventions, Boston Scientific
Day Two: Tuesday, May 2, 2017
FOCUS SESSION: Japan Today: Advancing Cardiometabolic Therapies
- Moderator: Masanori Aikawa, MD, PhD, Yoshiro Miwa Associate Chair and Founding Director, Center for Interdisciplinary Cardiovascular Sciences, BWH
- Carsten Brunn, PhD, Head of Pharmaceuticals, Americas Region, Bayer
- Hiroyuki Kawabata, Director, Health & Welfare Department, JETRO New York
- Makoto Suematsu, MD, PhD, President, Japan Agency for Medical Research and Development
- Eiji Tanaka, PhD, President, Head of Global Business Development, Mitsubishi Tanabe Pharma Holdings America, Inc.
Pricing to Enable Affordability and Innovation
- Moderator: Peter Slavin, MD, President, MGH
- Katrina Armstrong, MD, Physician-in-Chief, Department of Medicine, MGH; Jackson Professor of Clinical Medicine, Harvard Medical School
- George Barrett, CEO, Cardinal Health
- Paul Fonteyne, CEO, Boehringer Ingelheim USA
- Robert Ford, EVP, Medical Devices, Abbott
- Benjamin Scirica, MD, Director of Innovation, Cardiovascular Division, Senior Investigator, TIMI Study Group, BWH; Associate Professor of Medicine, Harvard Medical School
CLINICAL HIGHLIGHT: Emerging Devices for Complex Structural Heart Disease
- Moderator: Jason Mills, Managing Director, Head of US Healthcare Research, Canaccord Genuity
- Michael Dale, Divisional Vice President and General Manager, Structural Heart, Abbott
- Ian Meredith, PhD, EVP, Global CMO, Boston Scientific
- Patrick O’Gara, MD, Director, Clinical Cardiology, Executive Medical Director, BWH; Professor of Medicine, Harvard Medical School
- Stanton Rowe, CVP, Advanced Technology, CSO, Edwards Lifesciences
- Sean Salmon, SVP and President, Coronary & Structural Heart, Medtronic
1:1 Fireside Chat: John Lechleiter, PhD, Chairman, Eli Lilly
- Moderator: Susan Dentzer, CEO, Network for Excellence in Health Innovation
- John Lechleiter, PhD, Chairman, Eli Lilly and Company
Personal Monitoring for Disease Management
- Moderator: Joe Kvedar, MD, VP, Connected Health, Partners HealthCare; Associate Professor of Dermatology, Harvard Medical School
- Adam Landman, MD, CIO, VP, BWH; Course Co-Director, Harvard Medical School
- Michael Reitermann, COO, Siemens Healthineers
- Jonathan Rennert, CEO, Zoll Medical
- Stanley Shaw, MD, PhD, CSO, One Brave Idea, BWH; Associate Dean for Executive Education, Harvard Medical School
1:1 Fireside Chat: Robert Bradway, CEO, Amgen
- Moderator: Scott Sperling, Co-President, Thomas H Lee Partners
- Robert Bradway, CEO, Amgen
- Brigham and Women’s Hospital Winner: Benjamin Olenchock, MD, PhD, Cardiovascular Medicine Specialist, BWH; Instructor in Medicine, Harvard Medical School
- Massachusetts General Hospital Winner:
Steven Lubitz, MD, Cardiac Electrophysiologist, MGH; Assistant Professor of Medicine, Harvard Medical School
Global Clinical Trials: Next Generation Design and Scalability
- Moderator: Marc Sabatine, MD, Chairman, TIMI Study Group, Lewis Dexter, MD Distinguished Chair in Cardiovascular Medicine, BWH
- Elisabeth Björk, MD, PhD, VP, Cardiovascular & Metabolic Disease Head, Global Medicines Development, AstraZeneca
- Daniel Bloomfield, MD, SVP, Global Clinical Research, Therapeutic Area Head, Cardiometabolic & Womens Health, MRL Lead, China R&D, Merck
- Jonathan Plehn, MD, VP Cardiovascular Medicine, Covance
- Norman Stockbridge, MD, PhD, Director, Division of Cardiovascular and Renal Products, Food and Drug Administration
- Scott Wasserman, MD, VP, Global Development, Amgen
Precision Cardiovascular Medicine: What is Different This Time
- Moderator: Alex de Winter, PhD, Managing Director, GE Ventures
- Sean Harper, MD, EVP, R&D, Amgen
- Kevin Hrusovsky, CEO, Quanterix
- Dean Li, MD, PhD, VP, Head Translational Medicine, Merck
- David Milan, MD, Assistant in Medicine, MGH; Assistant Professor, Harvard Medical School
- Christine Seidman, MD, Director, Cardiovascular Genetics Center, BWH; Thomas W. Smith Professor
CV Investing in the Next Decade
- Moderator: Meg Tirrell, Reporter, CNBC
- Leslie Bottorff, Managing Director, Healthcare, GE Ventures
- Jean-François Formela, MD, Partner, Atlas Venture
- Bob Hopkins, Managing Director, US Medical Technology, Equity Research, Bank of America Merrill Lynch
- Roger Kitterman, VP, Venture, Partners HealthCare
- James Topper, MD, PhD, Managing General Partner, Frazier Healthcare Partners
CLINICAL HIGHLIGHT: Optimizing Care for the 51%: New Market Opportunities
- Moderator: Cathy Minehan, Managing Director, Arlington Advisory Partners
- Nancy Brown, CEO, American Heart Association
- Christine Albert, MD, Center for Arrhythmia Prevention, BWH; Professor of Medicine, Harvard Medical School
- Adele Gulfo, EVP & Head, Global Commercial Development, Mylan
- Allison Kean, MD, CV Therapeutic Area Lead, Global Business Development, Pfizer
- Paul Underwood, MD, Medical Director, Boston Scientific
- Malissa Wood, MD, Co-Director, MGH Heart Center Corrigan Women’s
Disruptive Therapeutic Platforms: New Tools, New Outcomes
- Moderator: Tony Coles, MD, CEO, Yumanity Therapeutics
- Stéphane Bancel, CEO, Moderna
- Katrine Bosley, CEO, Editas Medicine
- Mark Cobbold, MD, PhD, Center for Cancer Immunology, MGH; Member of the Faculty of Medicine, Harvard Medical School
- John Maraganore, PhD, CEO, Alnylam
- Ryuichi Morishita, MD, PhD, Founder, AnGes
Wednesday, May 3, 2017
1:1 Fireside Chat: Robert Califf, MD, Commissioner (former), FDA
- Moderator: Joseph Loscalzo, MD, PhD, Chairman, Department of Medicine, Physician-in-Chief, BWH; Hersey Professor of the Theory and Practice of Medicine, Soma Weiss, MD Distinguished Chair in Medicine, Harvard Medical School
- Robert Califf, MD, Commissioner (former), Food and Drug Administration
Innovation in Translational Trials
- Moderator: Mason Freeman, MD, Director, Translational Research Center, MGH; Professor of Medicine, Harvard Medical School
- Seigo Izumo, MD, SVP, Global Head of Regenerative Medicine Unit, Head of Scientific Affairs, Japan, Takeda
- John Lepore, MD, SVP, R&D Pipeline, GlaxoSmithKline
- Jessica Mega, MD, CMO, Verily
- Alan Moses, MD, SVP, Global CMO, Novo Nordisk
- Sy Pretorius, MD, SVP & CSO, PAREXEL International
1:1 Fireside Chat: Michael Mahoney, CEO, Boston Scientific
- Introducer: Edward Lawrence, Chairman, Board of Directors, Partners HealthCare; Retired Partner, Ropes & Gray
- Meg Tirrell, Reporter, CNBC
- Michael Mahoney, CEO, Boston Scientific
New Targets in Coronary Artery Disease
- Moderator: Sekar Kathiresan, MD, Director, Center for Human Genetic Research, MGH; Associate Professor of Medicine, Harvard Medical School
- Aarif Khakoo, MD, VP Research, Cardiometabolic Disorders Therapeutic Area Head, Site Head Amgen San Francisco, Amgen
- Clive Meanwell, MD, PhD, CEO, The Medicines Company
- Paul Ridker, MD, Director, Center for Cardiovascular Disease Prevention, BWH; Eugene Braunwald Professor of Medicine, Harvard Medical School
- Craig Sponseller, MD, CMO, Kowa Pharmaceuticals
1:1 Fireside Chat: Gary Gibbons, MD, NHLBI
- Moderator: Elizabeth Nabel, MD, President, Brigham Health; Professor of Medicine, Harvard Medical School
- Gary Gibbons, MD, Director, NHLBI
The Skinny on Fat: Therapeutic Opportunities
- Moderator: Ora Pescovitz, MD, SVP and US Medical Leader, Eli Lilly and Company
- Morris Birnbaum, MD, PhD, SVP and CSO, CVMET, Pfizer
- Ludovic Helfgott, Global VP, Cardiovascular, Renal and Metabolism, AstraZeneca
- Thomas Hughes, PhD, CEO, Zafgen
- Lee Kaplan, MD, PhD, Director, Obesity, Metabolism & Nutrition Institute, MGH; Associate Professor, Harvard Medical School
- Bruce Spiegelman, PhD, Stanley J. Korsmeyer Professor of Cell Biology and Medicine, Dana-Farber Cancer Institute, Harvard Medical School
Sponsors
