Past Forum: 2023 - World Medical Innovation Forum
WMIF Main Site

Past Forum: 2023

Boston

Summary

The ninth annual World Medical Innovation Forum was at a new venue, Westin Seaport Boston.

This year, we gathered to discuss the extraordinary opportunities in CNS/Brain Health, Oncology, Inflammation & Immunology and the profound impact they will have on medicine. In more than thirty sessions over the course of three days, Mass General Brigham’s Harvard faculty, industry experts and leading investors and entrepreneurs explored the technologies and challenges as we continue to bring life-changing breakthroughs to our patients and millions around the world.

The World Medical Innovation Forum was established to reaffirm the importance of collaborative innovation—academia, industry and government working together to create solutions for medicine’s great challenges. Our goal is to provide actionable insights for Forum participants. We are grateful to the nearly 200 senior executives, investors, Harvard clinicians and investigators who shared their perspectives as speakers.

Speakers

Tazeen Ahmad 
Managing Director, Global Research, BofA Securities

Mark Albers, MD, PhD
Frank Wilkens Jr and Family Endowed Scholar in AD Research, MGH; Assistant Professor of Neurology, HMS

Fabrisia Ambrosio, PhD
Atlantic Charter Director of the Discovery Center for Musculoskeletal Recovery, Schoen Adams Research Institute, Spaulding Rehabilitation Hospital; Faculty, HMS

Paul Anderson, MD, PhD
Acting Chief Academic Officer, Mass General Brigham; Professor of Medicine, HMS

Rox Anderson, MD
Lancer Endowed Chair of Dermatology; Director, Wellman Center for Photomedicine, MGH; Professor of Dermatology, HMS

Brian Anderson, MD
Chief Digital Health Physician, MITRE

Steven Arnold, MD
Director, Alzheimer’s Clinical & Translational Research Unit, Translational Neurology Head & Managing Director, Interdisciplinary Brain Center, MGH; Professor of Neurology, HMS

Natalie Artzi, PhD
Associate Bioengineer, BWH; Associate Professor of Medicine, HMS

Lindsey Baden, MD
Vice President Clinical Research, BWH; Professor, HMS

Chip Baird
CFO, 2seventy bio

Tom Barnes, PhD
CEO, Orna Therapeutics

Elisabeth Battinelli, MD, PhD
Physician, BWH; Associate Professor, HMS

James Berry, MD
Neurologist/ALS Clinical Researcher, MGH; Associate Professor, HMS

John Bishai, PhD
Managing Director, Healthcare Investment Banking, BofA Securities

Stephen Brady
CEO, Tempest Therapeutics

Diana Brainard, MD
CEO, AlloVir

Andy Bressler
Managing Director, Global Research, BofA Securities

Remy Brim, PhD
Principal, BGR Group

David Brown, MD
President, Mass General Hospital; MGH Trustees Professor of Emergency Medicine, HMS

Cait Brumme
CEO, MassChallenge

Greg Butz
Managing Director, Co-Head, North American Healthcare Investment Banking, Head of Life Sciences Investment Banking, BofA Securities

Robert Califf, MD
Commissioner, US Food and Drug Administration

Ruth Carlos, MD
Professor of Radiology, University of Michigan

Sree Chaguturu, MD
Senior Vice President and Chief Medical Officer CVS Health

Li Chai, MD
Pathologist and Principal Investigator, BWH; Associate Professor of Pathology, HMS

Miceal Chamberlain
President, Massachusetts, Bank of America

Janice Chen, PhD
Co-Founder & CTO, Mammoth Biosciences

Michael Cherny
Managing Director, Senior Equity Research Analyst, BofA Securities

Susan Chor
Equity Research Associate, BofA Securities

Chris Coburn
Chief Innovation Officer, Mass General Brigham

Joshua Cohen
Co-CEO, Amylyx Pharmaceuticals

Karen Costenbader, MD
Director, Lupus Program, BWH; Professor of Medicine, HMS

Merit Cudkowicz, MD
Chair, Department of Neurology, MGH; Julieanne Dorn Professor of Neurology, HMS

Olivier Danos, PhD
EVP and Chief Scientific Officer, REGENXBIO

Steve Davis
CEO, Acadia Pharmaceuticals

Shawn Demehri, MD, PhD
Director, High Risk Skin Cancer Clinic, MGH; MGH Research Scholar; Associate Professor, HMS

Ann DeWitt, PhD
General Partner, The Engine

Synho Do, PhD
Director, Lab of Medical Imaging and Computation, Mass General Brigham; Assistant Professor, HMS

Gerard Doherty, MD
Surgeon-in-Chief, BWH; Moseley Professor of Surgery, HMS

Mikael Dolsten, MD, PhD
Chief Scientific Officer & President, Worldwide Research, Development and Medical, Pfizer

Chadi El Saleeby, MD
Associate Pediatrician, Mass General for Children; Assistant Professor of Pediatrics, HMS

Conor Evans, PhD
Principal Investigator, Wellman Center for Photomedicine, MGH; Associate Professor, HMS

Maurizio Fava, MD
Chair of Psychiatry, MGH; Slater Family Professor of Psychiatry, HMS

Florian Fintelmann, MD
Radiologist, Physician-Scientist, MGH; Associate Professor of Radiology, HMS

Keith Flaherty, MD
Director of Clinical Research, Mass General Cancer Center; Professor of Medicine, HMS

Jean-François Formela, MD
Partner, Atlas Venture

Pat Fortune, PhD Vice President, Strategic Innovation Leaders, Mass General Brigham Innovation

Said Francis
SVP, Business Development and Corporate Strategy, Moderna

Johannes Fruehauf, MD, PhD
Founder & General Partner, Mission BioCapital; Co-Founder & President, LabCentral; CEO, BioLabs

Niyum Gandhi
Chief Financial Officer, Mass General Brigham

Michael Gapen, PhD
Head of US Economics Research, Bank of America

Arpa Garay
Chief Commercial Officer, Moderna

Lilit Garibyan, MD, PhD
Physician-Scientist, Wellman Center for Photomedicine, MGH; Associate Professor of Dermatology, HMS

Deborah Geraghty, PhD
President & CEO, Anokion

Jason Gerberry
Biopharma Equity Research Analyst, Bank of America

Laura Germine, PhD
Co-Director of the Institute for Technology in Psychiatry, President of the Many Brains Project, McLean Hospital; Associate Professor of Psychiatry, HMS

Craig Gordon, MD
Founder, CEO & CIO, GordonMD Global Investments

Scott Gottlieb, MD
Former Commissioner, Food and Drug Administration (2017-2019)

Ellen Gravallese, MD
Chief of Rheumatology, Inflammation, and Immunity, BWH; Theodore Bevier Bayles Professor of Medicine, HMS

Steven Greenberg, MD
Neurologist, BWH; Professor of Neurology, HMS

Daniel Haber, MD, PhD
Director, Mass General Cancer Center; Kurt J. Isselbacher Professor of Oncology, HMS

Roger Hajjar, MD
Director, Gene & Cell Therapy Institute Mass General Brigham

Alexandria Hammond, PhD
Vice President, Global Research, BofA Securities

Yvonne Hao
Secretary of Economic Development, Commonwealth of Massachusetts

Adam Harpool
Principal, Health & Digital, Oliver Wyman

Steve Harr, MD
President & CEO, Sana Biotechnology

Greg Harrison
Vice President, Global Research, BofA Securities

Maura Healey
Governor of the Commonwealth of Massachusetts

Adi Hoess, MD, PhD
CEO, Affimed

Natalie Holles
CEO, Third Harmonic Bio

Zachary Hornby
CEO, Boundless Bio

Tom Hubbard
Senior Vice President, Network for Excellence in Health Innovation (NEHI)

Ole Isacson, MD, PhD
Director, Neuroregeneration Research Institute, McLean Hospital; Professor of Neurology and Neuroscience, HMS

Tatjana Jakobs, MD
Associate Scientist, Schepens Eye Research Institute of Mass Eye and Ear; Associate Professor of Ophthalmology, HMS

Russell Jenkins, MD, PhD
Investigator, Center for Cancer Research, MGH; Assistant Professor of Medicine, HMS

Kevin Judice, PhD
CEO & Founder, DICE Therapeutics

Rosana Kapeller, MD, PhD
CEO, ROME Therapeutics

Barry Kappel, PhD
Founder, President & CEO, Sapience Therapeutics

Tariq Kassum, MD
CEO, Celsius Therapeutics

Keith Kerman, MD 
Operating Partner & Senior Advisor, The Riverside Company

Rachna Khosla
Senior Vice President, Business Development, Amgen

Roger Kitterman
Senior Vice President, Venture, Business Development and Licensing, Mass General Brigham

Justin Klee
Co-CEO, Amylyx Pharmaceuticals

Anne Klibanski, MD
President & CEO, Mass General Brigham

Adam Koppel, MD, PhD
Partner, Bain Capital Life Sciences

Vesela Kovacheva, MD, PhD
Director of Translational and Clinical Research, BWH; Assistant Professor of Anesthesia, HMS

Jonathan Kraft
President, The Kraft Group; Chairman, Board of Trustees, MGH

Vijay Kuchroo, DMV, PhD
Director, Evergrande Center for Immunologic Diseases, BWH; Samuel L. Wasserstrom Professor of Neurology, HMS

Clotilde Lagier-Tourenne, MD, PhD
Araminta Broch-Healey Endowed Chair in ALS, MGH; Associate Professor of Neurology, HMS

Adam Landman, MD
Chief Information Officer and Senior Vice President, Digital, Mass General Brigham Associate Professor of Emergency Medicine, HMS

Corinne Le Goff, PharmD
President & CEO, Imunon

Nicole LeBoeuf, MD
Chief of Oncodermatology, BHW; Vice Chair of Dermatology, Dana-Farber Brigham Cancer Center; Associate Professor of Dermatology, HMS

John Lepore, MD
SVP, Head of Research, GSK

Zhen Li, PhD
President & CEO, ADARx Pharmaceuticals

Katherine Liao, MD
Associate Physician, Department of Rheumatology, Inflammation, and Immunity, BWH; Associate Professor of Medicine and Biomedical Informatics, HMS

Evan Lippman
Chief Corporate Development & Strategy Officer, Alnylam

Bill Lundberg, MD
CEO, Merus

Ivana Magovcevic-Liebisch, PhD
President & CEO, Vigil Neuroscience

David Main
CEO, Notch Therapeutics

Tanya Mayadas, PhD
Senior Staff Scientist, BWH; Professor of Pathology, HMS

Ralph Mazitschek, PhD
Principal Investigator, MGH Assistant Professor, HMS

Geoff Meacham, PhD
Managing Director, Global Research, BofA Securities

Aamir Mecklai
Managing Director, Healthcare Investment Banking, BofA Securities

Adrian Mee
Managing Director, Head of Global Healthcare Investment Banking, BofA Securities

Vimal Mehta, MD
CEO, BioXcel Therapeutics

Joan Miller, MD
Chief of Ophthalmology, Mass Eye and Ear and MGH; Ophthalmologist-in-Chief, BWH; David Glendenning Cogan Professor of Ophthalmology, HMS

Jodie Morrison
CEO, Q32 Bio

Brian Moynihan
Chair & CEO, Bank of America

Sumit Mukherjee
Managing Director, Co-Head of Origination, Americas Equity Capital Markets, BofA Securities

Peter Neumann, ScD
Director-CEVR, Tufts Medical Center

Steven Pearson, MD
President, Institute for Clinical and Economic Review; Lecturer, Department of Population Medicine, HMS

James Porter, PhD
CEO, Nuvalent

Yakeel Quiroz, PhD
Director, Familial Dementia Neuroimaging Lab and Director, Multicultural Alzheimer’s Prevention Program, MGH; Paul B. and Sandra M. Edgerley MGH Research Scholar; Associate Professor, HMS

Noopur Raje, MD
Director, Center for Multiple Myeloma, Mass General Cancer Center; Professor of Medicine, HMS

Kerry Ressler, MD, PhD
Chief Scientific Officer, McLean Hospital; Professor of Psychiatry, HMS

Lisa Ricciardi
President & CEO, Cognition Therapeutics

Ryan Richardson
Chief Strategy Officer, BioNTech

David Ricks
Chair & CEO, Eli Lilly and Company

Kasper Roet, PhD 
CEO & Co-Founder, QurAlis

Cheryl Sadro
Chief Financial Officer, UC Davis Health

Robert Scannevin, PhD
Chief Scientific Officer, Verge Genomics

Andrew Schiermeier, PhD
President & CEO, AvenCell Therapeutics

Thomas Schuetz, MD, PhD
CEO & Co-Founder, Compass Therapeutics

Fred Schwarzer
CEO, IGM Biosciences

Lynn Seely, MD
President & CEO, Lyell

Stephanie Seminara, MD
Chief, Reproductive Endocrine Unit, MGH; Professor of Medicine, HMS

Laura Sepp-Lorenzino, PhD
Executive Vice President, Chief Scientific Officer, Intellia Therapeutics

Nimish Shah
Partner, Venrock

Munjal Shah
Co-Founder & CEO, Hippocratic AI

Angela Shen, MD
Vice President, Strategic Innovation Leaders, Mass General Brigham Innovation

Samantha Singer
President & CEO, Abata Therapeutics

Varun Singh, PhD
President & Co-Founder, Moveworks

Jordan Smoller, MD, ScD
Associate Chief for Research and Director, Center for Precision Psychiatry, Department of Psychiatry, MGH; Tepper Family MGH Research Scholar; Professor of Psychiatry, HMS

Jeffrey Sparks, MD
Associate Physician, BWH; Associate Professor of Medicine, HMS

Paula Ness Speers
Co-Founder & Senior Advisor, Health Advances

Scott Sperling
Co-CEO, Thomas H. Lee Partners; Chairman of the Board, Mass General Brigham

Jason Springs
Co-Founder & CEO, Endpoint Health

Catherine Stehman-Breen, MD
CEO, Chroma Medicine

Alec Stranahan, PhD
Vice President, Global Research, BofA Securities

Marc Succi, MD
Executive Director, Mass General Brigham MESH Incubator; Associate Chair of Innovation & Commercialization, Mass General Brigham Radiology; Strategic Innovation Leader, Mass General Brigham Innovation

Rudolph Tanzi, PhD
Director, Genetics and Aging Research Unit, Co-Director, McCance Center for Brain Health, MGH; Joseph P. and Rose F. Kennedy Professor of Neurology, HMS

David Ting, MD
Associate Clinical Director for Innovation, Mass General Cancer Center; Associate Professor of Medicine, HMS

Meg Tirrell
Medical Correspondent, CNN

R. Nolan Townsend
CEO, LEXEO Therapeutics

Andre Turenne
CEO, Matchpoint Therapeutics

Chris Viehbacher
President & CEO, Biogen

Brian Wainger, MD, PhD
Trustees Endowed Scholar in Anesthesia and Alexander Healey Endowed Chair in ALS, Neurology & Anesthesia, Critical Care and Pain Medicine, MGH; Associate Professor, HMS

Robert Waldinger, MD
Director, Harvard Study of Adult Development, MGH; Professor of Psychiatry, HMS

Kate Walsh
Secretary of Health and Human Services, State of Massachusetts

Philip Wang, MD, DrPH
Director of the Center for Learning Health Systems, BWH; Professor of the Practice of Psychiatry, HMS

Brittany Weber, MD, PhD
Director, Cardio-Rheumatology Clinic, Associate Physician, Prevention Cardiology and Cardiovascular Imaging, BWH; Instructor of Medicine, HMS

Renee Wegrzyn, PhD
Director, Advanced Research Projects Agency for Health

Rachel Whooten, MD
Pediatric Endocrinologist, MGH; Assistant Professor, HMS

Troy Wilson, PhD
President & CEO, Kura Oncology

Charlie Yang, PhD
Vice President, US Biopharmaceutical Equity Research Analyst, BofA Securities

Jason Zemansky, PhD
Vice President, Global Research, BofA Securities

Panels

Monday, June 12, 2023

First Look: 8 rapid fire presentations

  • Moderator: Paul Anderson, MD, PhD, Acting Chief Academic Officer, Mass General Brigham; Professor of Medicine, HMS
  • Moderator: Roger Kitterman, Senior Vice President, Venture, Business Development and Licensing, Mass General Brigham

Presenters:

  • Mark Albers, MD, PhD, Frank Wilkens Jr and Family Endowed Scholar in AD Research, MGH; Assistant Professor of Neurology, HMS
  • Yakeel Quiroz, PhD, Director, Familial Dementia Neuroimaging Lab and Director, Multicultural Alzheimer’s Prevention Program, MGH; Paul B. and Sandra M. Edgerley MGH Research Scholar; Associate Professor, HMS
  • Tanya Mayadas, PhD, Senior Staff Scientist, BWH; Professor of Pathology, HMS
  • Synho Do, PhD, Director, Lab of Medical Imaging and Computation, Mass General Brigham; Assistant Professor, HMS
  • Tatjana Jakobs, MD, Associate Scientist, Schepens Eye Research Institute of Mass Eye and Ear; Associate Professor of Ophthalmology, HMS
  • Russell Jenkins, MD, PhD, Investigator, Center for Cancer Research, MGH; Assistant Professor of Medicine, HMS
  • Clotilde Lagier-Tourenne, MD, PhD, Araminta Broch-Healey Endowed Chair in ALS, MGH; Associate Professor of Neurology, HMS
  • Kerry Ressler, MD, PhD, Chief Scientific Officer, McLean Hospital; Professor of Psychiatry, HMS

First Look: 8 rapid fire presentations

  • Moderator: Paul Anderson, MD, PhD, Acting Chief Academic Officer, Mass General Brigham; Professor of Medicine, HMS
  • Moderator: Roger Kitterman, Senior Vice President, Venture, Business Development and Licensing, Mass General Brigham

Presenters:

  • Fabrisia Ambrosio, PhD, Atlantic Charter Director of the Discovery Center for Musculoskeletal Recovery, Schoen Adams Research Institute, Spaulding Rehabilitation Hospital; Faculty, HMS
  • Li Chai, MD, Pathologist and Principal Investigator, BWH; Associate Professor of Pathology, HMS
  • Angela Shen, MD, Vice President, Strategic Innovation Leaders, Mass General Brigham Innovation
  • Ralph Mazitschek, PhD, Principal Investigator, MGH Assistant Professor, HMS
  • Shawn Demehri, MD, PhD, Director, High Risk Skin Cancer Clinic, MGH; MGH Research Scholar; Associate Professor, HMS
  • Brian Wainger, MD, PhD, Trustees Endowed Scholar in Anesthesia and Alexander Healey Endowed Chair in ALS, Neurology & Anesthesia, Critical Care and Pain Medicine, MGH; Associate Professor, HMS
  • Jordan Smoller, MD, ScD, Associate Chief for Research and Director, Center for Precision Psychiatry, Department of Psychiatry, MGH; Tepper Family MGH Research Scholar; Professor of Psychiatry, HMS
  • Natalie Artzi, PhD, Associate Bioengineer, BWH; Associate Professor of Medicine, HMS

Biopharmaceuticals and The Inflation Reduction Act: A Status Report on IRA Implementation

  • Moderator: Tom Hubbard, Senior Vice President, Network for Excellence in Health Innovation (NEHI)
    Panelists
  • Peter Neumann, ScD, Director-CEVR, Tufts Medical Center
  • Steven Pearson, MD, President, Institute for Clinical and Economic Review; Lecturer, Department of Population Medicine, HMS

The Inflation Reduction Act: The Emerging Implications for Biopharmaceutical Innovation 

  • Moderator: Tom Hubbard, Senior Vice President, Network for Excellence in Health Innovation (NEHI)
    Panelists
  • Stephen Brady, CEO, Tempest Therapeutics
  • Remy Brim, PhD, Principal, BGR Group
  • Pat Fortune, PhD, Vice President, Strategic Innovation Leaders, Mass General Brigham Innovation
  • John Lepore, MD, SVP, Head of Research, GSK
THE DR. IS IN | Mental Health Clinical Trials | Measurable vs. Hype
  • Moderator: Kerry Ressler, MD, PhD, Chief Scientific Officer, McLean Hospital; Professor of Psychiatry, HMS
  • Laura Germine, PhD, Co-Director of the Institute for Technology in Psychiatry, President of the Many Brains Project, McLean Hospital; Associate Professor of Psychiatry, HMS
  • Philip Wang, MD, DrPH, Director of the Center for Learning Health Systems, BWH; Professor of the Practice of Psychiatry, HMS

THE DR. IS IN | The Future of Academic Medical Centers | Economic Challenges, Adaptation, and Opportunities 

  • Moderator: Niyum Gandhi, Chief Financial Officer, Mass General Brigham
  • Andrew Bressler, Managing Director, Global Research, BofA Securities
  • Adam Harpool, Principal, Health & Digital, Oliver Wyman
  • Cheryl Sadro, Chief Financial Officer, UC Davis Health

THE DR. IS IN | Academic Innovation’s Citadel | Wellman Center’s Unrivaled Translation

  • Moderator: Rox Anderson, MD, Lancer Endowed Chair of Dermatology; Director, Wellman Center for Photomedicine, MGH; Professor of Dermatology, HMS
  • Conor Evans, PhD, Principal Investigator, Wellman Center for Photomedicine, MGH; Associate Professor, HMS
  • Lilit Garibyan, MD, PhD, Physician-Scientist, Wellman Center for Photomedicine, MGH; Associate Professor of Dermatology, HMS
THE DR. IS IN | Biotech Deal Making Draws Increasingly on Accelerators and Incubators Especially in America’s Innovation Hub
  • Moderator: Roger Kitterman, Senior Vice President, Venture, Business Development and Licensing, Mass General Brigham
  • Cait Brumme, CEO, MassChallenge Ann DeWitt, PhD, General Partner, The Engine
  • Johannes Fruehauf, MD, PhD, Founder & General Partner, Mission BioCapital; Co-Founder & President, LabCentral; CEO, BioLabs
  • Marc Succi, MD, Executive Director, Mass General Brigham MESH Incubator; Associate Chair of Innovation & Commercialization, Mass General Brigham Radiology; Strategic Innovation Leader, Mass General Brigham Innovation

THE DR. IS IN | Inflammation and Immunology: Balancing the Risks and Rewards of Immune System Modulation in Treatment

  • Moderator: Katherine Liao, MD, Associate Physician, Department of Rheumatology, Inflammation, and Immunity, BWH; Associate Professor of Medicine and Biomedical Informatics, HMS
  • Moderator: Jeffrey Sparks, MD, Associate Physician, BWH; Associate Professor of Medicine, HMS
  • Nicole LeBoeuf, MD, Chief of Oncodermatology, BHW; Vice Chair of Dermatology, Dana-Farber Brigham Cancer Center; Associate Professor of Dermatology, HMS
  • Brittany Weber, MD, PhD, Director, Cardio-Rheumatology Clinic, Associate Physician, Prevention Cardiology and Cardiovascular Imaging, BWH; Instructor of Medicine, HMS

THE DR. IS IN | Generative AI, ChatGPT, and the Rapidly Changing Role of AI in Healthcare

  • Moderator: Adam Landman, MD, Chief Information Officer and Senior Vice President, Digital, Mass General Brigham Associate Professor of Emergency Medicine, HMS
  • Brian Anderson, MD, Chief Digital Health Physician, MITRE
  • Ruth Carlos, MD, Professor of Radiology, University of Michigan
  • Munjal Shah, Co-Founder & CEO, Hippocratic AI
  • Varun Singh, PhD, President & Co-Founder, Moveworks

Opening Remarks

  • Introducer: Scott Sperling, Co-CEO, Thomas H. Lee Partners; Chairman of the Board, Mass General Brigham
  • Moderator: Jonathan Kraft, President, The Kraft Group; Chairman, Board of Trustees, MGH
  • Anne Klibanski, MD, President & CEO, Mass General Brigham
  • Brian Moynihan, Chair & CEO, Bank of America

Opening Remarks 

  • Maura Healey, Governor of the Commonwealth of Massachusetts

1:1 Fireside Chat 

  • Moderator: Meg Tirrell, Medical Correspondent, CNN
  • Chris Viehbacher, President & CEO, Biogen

The Disruptors: The Next Wave of Promising Psychiatry and Neurology Drugs

  • Moderator: Maurizio Fava, MD, Chair of Psychiatry, MGH; Slater Family Professor of Psychiatry, HMS
  • Moderator: Greg Harrison, Vice President, Global Research, BofA Securities
  • Joshua Cohen, Co-CEO, Amylyx Pharmaceuticals
  • Steve Davis, CEO, Acadia Pharmaceuticals
  • Justin Klee, Co-CEO, Amylyx Pharmaceuticals
  • Ivana Magovcevic-Liebisch, PhD, President & CEO, Vigil Neuroscience
  • Vimal Mehta, MD, CEO, BioXcel Therapeutics

The Science of Happiness

  • Moderator: Rudolph Tanzi, PhD, Director, Genetics and Aging Research Unit, Co-Director, McCance Center for Brain Health, MGH; Joseph P. and Rose F. Kennedy Professor of Neurology, HMS
  • Robert Waldinger, MD, Director, Harvard Study of Adult Development, MGH; Professor of Psychiatry, HMS

The Innovation Gap: Dissecting Emerging Modalities and Mechanisms for Treating CNS Diseases

  • Moderator: Ole Isacson, MD, PhD, Director, Neuroregeneration Research Institute, McLean Hospital; Professor of Neurology and Neuroscience, HMS
  • Moderator: Charlie Yang, PhD, Vice President, US Biopharmaceutical Equity Research Analyst, BofA Securities
  • Lisa Ricciardi, President & CEO, Cognition Therapeutics
  • Kasper Roet, PhD, CEO & Co-Founder, QurAlis
  • Robert Scannevin, PhD, Chief Scientific Officer, Verge Genomics

A Deep Dive on Genetic Modalities for CNS Diseases: The Genetic Medicine Frontier and Applications in CNS

  • Moderator: Merit Cudkowicz, MD, Chair, Department of Neurology, MGH; Julieanne Dorn Professor of Neurology, HMS
  • Moderator: Aamir Mecklai, Managing Director, Healthcare Investment Banking, BofA Securities
  • Janice Chen, PhD, Co-Founder & CTO, Mammoth Biosciences
  • Olivier Danos, EVP and Chief Scientific Officer, REGENXBIO
  • Zhen Li, PhD, President & CEO, ADARx Pharmaceuticals
  • Catherine Stehman-Breen, MD, CEO, Chroma Medicine
  • R. Nolan Townsend, CEO, LEXEO Therapeutics

1:1 Fireside Chat

  • Moderator: David Brown, MD, President, Mass General Hospital; MGH Trustees Professor of Emergency Medicine, HMS
  • Kate Walsh, Secretary of Health and Human Services, State of Massachusetts

Fireside Chat

  • Moderator: Michael Cherny, Managing Director, Senior Equity Research Analyst, BofA Securities
  • Moderator: Niyum Gandhi, Chief Financial Officer, Mass General Brigham
  • Sree Chaguturu, MD, Senior Vice President and Chief Medical Officer CVS Health

Tuesday, June 13, 2023

Fireside Chat

  • Moderator: Geoff Meacham, PhD, Managing Director, Global Research, BofA Securities
  • Paula Ness, Speers Co-Founder & Senior Advisor, Health Advances
  • Arpa Garay, Chief Commercial Officer, Moderna

The Disruptors: The Biologic Revolution in Cancer Continues

  • Moderator: Daniel Haber, MD, PhD, Director, Mass General Cancer Center; Kurt J. Isselbacher Professor of Oncology, HMS
    Panelists
  • Bill Lundberg, MD, CEO, Merus
  • Thomas Schuetz, MD, PhD, CEO & Co-Founder, Compass Therapeutics
  • Fred Schwarzer, CEO, IGM Biosciences
The Innovation Gap: Crumblin’ Down – Driving Cell Therapy into Solid Tumors
  • Moderator: Tazeen Ahmad, Managing Director, Global Research, BofA Securities
  • Moderator: Angela Shen, MD, Vice President, Strategic Innovation Leaders, Mass General Brigham Innovation
  • Corinne Le Goff, PharmD, President & CEO, Imunon
  • Ryan Richardson, Chief Strategy Officer, BioNTech
  • Lynn Seely, MD, President & CEO, Lyell

A Deep Dive on Targeted Oncology: Small Molecule Discovery and Development Remains Robust

  • Moderator: Keith Flaherty, MD, Director of Clinical Research, Mass General Cancer Center; Professor of Medicine, HMS
  • Moderator: Jason Gerberry, Biopharma Equity Research Analyst, Bank of America
  • Stephen Brady, CEO, Tempest Therapeutics
  • Zachary Hornby, CEO, Boundless Bio
  • James Porter, PhD, CEO, Nuvalent

Capital Formation: Putting Money to Work – State of Affairs in Capital Markets

  • Moderator: Greg Butz, Managing Director, Co-Head, North American Healthcare Investment Banking, Head of Life Sciences Investment Banking, BofA Securities
  • Moderator: Yvonne Hao, Secretary of Economic Development, Commonwealth of Massachusetts
  • Moderator: Sumit Mukherjee, Managing Director, Co-Head of Origination, Americas Equity Capital Markets, BofA Securities
  • Jean-François Formela, MD, Partner, Atlas Venture
  • Craig Gordon, MD, Founder, CEO & CIO, GordonMD Global Investments
  • Roger Kitterman, Senior Vice President, Venture, Business Development and Licensing, Mass General Brigham
  • Nimish Shah, Partner, Venrock

Lunch & The Bigger Economic Picture

  • Moderator: Miceal Chamberlain, President, Massachusetts, Bank of America
  • Michael Gapen, PhD, Head of US Economics Research, Bank of America

Fireside Chat

  • Moderator: Geoff Meacham, PhD, Managing Director, Global Research, BofA Securities
  • David Ricks, Chair & CEO, Eli Lilly and Company

The Disruptors: What’s Next for Cell Therapy in Liquid Tumors?

  • Moderator: Noopur Raje, MD, Director, Center for Multiple Myeloma, Mass General Cancer Center; Professor of Medicine, HMS
  • Moderator: Alec Stranahan, PhD, Vice President, Global Research, BofA Securities
  • Chip Baird, CFO, 2seventy bio
  • Steve Harr, MD, President & CEO, Sana Biotechnology
  • Laura Sepp-Lorenzino, PhD, Executive Vice President, Chief Scientific Officer, Intellia Therapeutics
Fireside Chat
  • Introducer: Yvonne Hao, Secretary of Economic Development, Commonwealth of Massachusetts
  • Moderator: Andrew Bressler, Managing Director, Global Research, BofA Securities
  • Moderator: Adam Koppel, MD, PhD, Partner, Bain Capital Life Sciences
  • Renee Wegrzyn, PhD, Director, Advanced Research Projects Agency for Health

The Innovation Gap: The Promise of Precision Oncology for Liquid Tumors

  • Moderator: Elisabeth Battinelli, MD, PhD, Physician, BWH; Associate Professor, HMS
  • Moderator: John Bishai, PhD, Managing Director, Healthcare Investment Banking, BofA Securities
  • Adi Hoess, MD, PhD, CEO, Affimed
  • Barry Kappel, PhD, Founder, President & CEO, Sapience Therapeutics
  • Troy Wilson, PhD, President & CEO, Kura Oncology

A Deep Dive on Cell Therapy: Applying Lessons Learned from First-Generation Cell Therapies

  • Moderator: David Ting, MD, Associate Clinical Director for Innovation, Mass General Cancer Center; Associate Professor of Medicine, HMS
  • Moderator: Jason Zemansky, PhD, Vice President, Global Research, BofA Securities
  • Tom Barnes, PhD, CEO, Orna Therapeutics
  • David Main, CEO, Notch Therapeutics
  • Andrew Schiermeier, PhD, President & CEO, AvenCell Therapeutics

Fireside Chat

  • Moderator: Tazeen, Ahmad, Managing Director, Global Research, BofA Securities
  • Moderator: Lindsey Baden, MD, Vice President Clinical Research, BWH; Professor, HMS
  • Robert Califf, MD, Commissioner, US Food and Drug Administration

M&A and Business Development Roundtable: Who Wants to Make a Deal – Biopharma M&A/BD Perspectives

  • Moderator: Greg Butz, Managing Director, Co-Head, North American Healthcare Investment Banking, Head of Life Sciences Investment Banking, BofA Securities
  • Moderator: Adrian Mee, Managing Director, Head of Global Healthcare Investment Banking, BofA Securities
  • Said Francis, SVP, Business Development and Corporate Strategy, Moderna
  • Rachna Khosla, Senior Vice President, Business Development, Amgen
    Evan Lippman, Chief Corporate Development & Strategy Officer, Alnylam

Wednesday, June 14, 2023

Fireside Chat

  • Moderator: Keith Kerman, MD, Operating Partner & Senior Advisor, The Riverside Company
  • Moderator: Geoff Meacham, PhD, Managing Director, Global Research, BofA Securities
  • Scott Gottlieb, MD, Former Commissioner, Food and Drug Administration (2017-2019)

The Disruptors: Driving I&I Therapy Adoption with Oral Formulations

  • Moderator: Steven Greenberg, MD, Neurologist, BWH; Professor of Neurology, HMS
  • Natalie Holles, CEO, Third Harmonic Bio
  • Kevin Judice, PhD, CEO & Founder, DICE Therapeutics
  • Rosana Kapeller, MD, PhD, CEO, ROME Therapeutics
  • Andre Turenne, CEO, Matchpoint Therapeutics

The Innovation Gap: Old Dog, New Tricks – Reprogramming the Immune System

  • Moderator: Ellen Gravallese, MD, Chief of Rheumatology, Inflammation, and Immunity, BWH; Theodore Bevier Bayles Professor of Medicine, HMS
  • Moderator: Alexandria Hammond, PhD, Vice President, Global Research, BofA Securities
  • Diana Brainard, MD, CEO, AlloVir
  • Deborah Geraghty, PhD, President & CEO, Anokion
  • Samantha Singer, President & CEO, Abata Therapeutics

A Deep Dive on Newly Validated Modalities: The Pathway Less Traveled – Emerging Targets in I&I

  • Moderator: Susan Chor, Equity Research Associate, BofA Securities
  • Moderator: Karen Costenbader, MD, Director, Lupus Program, BWH; Professor of Medicine, HMS
  • Tariq Kassum, MD, CEO, Celsius Therapeutics
  • Jodie Morrison, CEO, Q32 Bio
  • Jason Springs, Co-Founder & CEO, Endpoint Health

Fireside Chat

  • Moderator: Vijay Kuchroo, DMV, PhD, Director, Evergrande Center for Immunologic Diseases, BWH; Samuel L. Wasserstrom Professor of Neurology, HMS
  • Moderator: Geoff Meacham, PhD, Managing Director, Global Research, BofA Securities
  • Mikael Dolsten, MD, PhD, Chief Scientific Officer & President, Worldwide Research, Development and Medical, Pfizer

Disruptive Dozen

  • Moderator: Paul Anderson, MD, PhD, Acting Chief Academic Officer, Mass General Brigham; Professor of Medicine, HMS
  • Moderator: Lilit Garibyan, MD, PhD, Physician-Scientist, Wellman Center for Photomedicine, MGH; Associate Professor of Dermatology, HMS
  • Moderator: Rudolph Tanzi, PhD, Director, Genetics and Aging Research Unit, Co-Director, McCance Center for Brain Health, MGH; Joseph P. and Rose F. Kennedy Professor of Neurology, HMS
  • Rachel Whooten, MD, Pediatric Endocrinologist, MGH; Assistant Professor, HMS
  • Steven Arnold, MD, Director, Alzheimer’s Clinical & Translational Research Unit, Translational Neurology Head & Managing Director, Interdisciplinary Brain Center, MGH; Professor of Neurology, HMS
  • Joan Miller, MD, Chief of Ophthalmology, Mass Eye and Ear and MGH; Ophthalmologist-in-Chief, BWH; David Glendenning Cogan Professor of Ophthalmology, HMS
  • Florian Fintelmann, MD, Radiologist, Physician-Scientist, MGH; Associate Professor of Radiology, HMS
  • David Ting, MD, Associate Clinical Director for Innovation, Mass General Cancer Center; Associate Professor of Medicine, HMS
  • Stephanie Seminara, MD, Chief, Reproductive Endocrine Unit, MGH; Professor of Medicine, HMS
  • Roger Hajjar, MD, Director, Gene & Cell Therapy Institute Mass General Brigham
  • Vesela Kovacheva, MD, PhD, Director of Translational and Clinical Research, BWH; Assistant Professor of Anesthesia, HMS
  • James Berry, MD, Neurologist/ALS Clinical Researcher, MGH; Associate Professor, HMS
  • Lindsey Baden, MD, Vice President Clinical Research, BWH; Professor, HMS
  • Chadi El Saleeby, MD, Associate Pediatrician, Mass General for Children; Assistant Professor of Pediatrics, HMS
  • Gerard Doherty, MD, Surgeon-in-Chief, BWH; Moseley Professor of Surgery, HMS

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May 11–13, 2020 | Boston, MA