Husseini K. Manji, MD, FRCPC is Global Therapeutic Head for Neuroscience at Janssen Research & Development, LLC, one of the Johnson & Johnson pharmaceutical companies. He is also Visiting Professor at Duke University. Dr. Manji was previously Chief of the Laboratory of Molecular Pathophysiology & Experimental Therapeutics at the National Institutes of Health (NIH) and Director of the NIH Mood and Anxiety Disorders Program, the largest program of its kind in the world.
The major focus of Dr. Manji’s world-renowned research is the investigation of disease- and treatment-induced changes in gene and protein networks that regulate synaptic and neural plasticity in neuropsychiatric disorders. His work has helped to conceptualize these illnesses as genetically-influenced disorders of synaptic and neural plasticity and has led to the investigation of novel therapeutics for refractory patients. Dr. Manji has also been actively involved in developing biomarkers to help refine these multifactoral diseases.
Dr. Manji has received a number of prestigious awards, including the NIMH Director’s Career Award for Significant Scientific Achievement, the A. E. Bennett Award for Neuropsychiatric Research, the Ziskind-Somerfeld Award for Neuropsychiatric Research, the NARSAD Mood Disorders Prize, the Mogens Schou Distinguished Research Award, the ACNP’s Joel Elkes Award for Distinguished Research, the DBSA Klerman Senior Distinguished Researcher Award, the American Federation for Aging Research Award of Distinction, the Global Health & the Arts Award of Recognition, and PhRMA’s Research & Hope Award for Excellence in Biopharmaceutical Research. In 2017, he was recognized as one of 14 inaugural “Health Heroes” by O, The Oprah Magazine.
Dr. Manji has been inducted into the National Academy of Sciences’ Institute of Medicine (IOM) and has held numerous leadership positions within the IOM, the NIH Biomarkers Neuroscience Steering Committee, the ACNP, and the Society of Biological Psychiatry.
Throughout his career, Dr. Manji has also been committed to undertakings related to medical and neuroscience education and has worked with the National Board of Medical Examiners (NMBE), the Howard Hughes Medical Institute Research Scholars Program, and numerous national curriculum committees. He founded and co-directed the NIH Foundation for the Advanced Education in the Sciences Graduate Course in the Neurobiology of Neuropsychiatric Illness, and has received several teaching and mentoring awards. In addition to serving on the editorial board of numerous journals, Dr. Manji has been Editor of Neuropsychopharmacology Reviews, Deputy Editor of Biological Psychiatry, and Associate Editor of Bipolar Disorders.