Dr. Calum MacRae is a cardiologist, geneticist, and developmental biologist. He is Professor of Medicine at Harvard Medical School, Director of One Brave Idea at Brigham and Women’s Hospital, an Associate Member at the Broad Institute and a Principal Faculty member at the Harvard Stem Cell Institute. His research is focused on understanding the fundamental mechanisms of disease, using human studies and complementary systems-level modeling in model organisms and stem cells. He co-leads a national drug discovery consortium focused on environmental threats, he is the Principal Investigator of the Apple Health Study and has extensive experience in the integration of novel tools and devices at the interface between biology and technology. He is a co-founder of Atman Health and Tanaist Bio and is a board member at TMA Precision Health and LifeMD. His clinical interests include general cardiology, genomic medicine, innovation in phenotyping, and the redesign of clinical care.