What if we could prevent up to 40% of dementia cases, 60% of strokes, and 35% of depression—before they even start? In this episode, Dr. Jonathan Rosand, a neurologist and co-founder of the McCance Center for Brain Health at Mass General Brigham, joins us to discuss the McCance Brain Care Score—a powerful new tool designed to measure and improve lifelong brain health.

We explore the science behind brain disease prevention, the challenges of translating risk into action when mechanisms remain uncertain, and why brain care must become a global movement. From digital health to social change, this conversation dives into the urgent need to shift from reactive treatment to proactive brain resilience—and what it will take to get there.