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Past Forum 2017

Summary

Where High-Impact Global Initiatives Begin

The World Neuroscience Innovation Forum was a tailored, neuroscience gathering that built on the broad success of the flagship Annual Forums. The Neuroscience Forum took place in London at the Francis Crick Institute on 27 March 2017. It featured highly-interactive exchanges among neuroscience leaders, with the aim of turning insights into action. The Forum was being jointly hosted by Partners HealthCare and the Francis Crick Institute. It was a collaboration among them, leading pharmaceutical and biotechnology companies, investors and other academic centers. The goal of the Forum is to spark new insights, therapeutic paths and collaborations to combat neuroinflammation and neurodegeneration. The Forum convened international leaders from throughout the neuroscience community, including principals from the corporate, academic, government, foundation and investment sectors. The objectives:

  • Launch focused translation and commercialization collaborations to address unmet needs.
  • Seed new and grow world-class international neuroscience teams that will lead to high impact commercial products.
  • Initiate Springboard Challenge designed to position new international commercialization-oriented teams for substantial industry, government and philanthropic support.
  • Increase interactions among top neuro-oriented investigators, investors, entrepreneurs, corporate leaders, philanthropists and government executives across Europe and in the US.

2017 Resources

Program Book

Keynoters

Merit Cudkowicz, MD

Chair, Department of Neurology, MGH; – Julieanne Dorn Professor of Neurology, HMS

Michael Ehlers, MD, PhD

EVP, Head of R&D, Biogen

Hilary Evans

CEO, Alzheimer’s Research UK

Jean-François Formela, MD

Partner, Atlas Venture

Michael Hayden, MD, PhD

Anne Heatherington, PhD

SVP, Head of Data Sciences Institute, Takeda

Michael Hutton, PhD

CSO, Neuroscience, Eli Lilly and Company

Brad Hyman, MD, PhD

Director, MGH Alzheimer’s Disease Research Center, MGH; – John B. Penny, Jr. Professor of Neurology, HMS

Ole Isacson, MD, PhD

Director, Neuroregeneration Research Institute, McLean Hospital; – Professor of Neurology and Neuroscience, HMS

Anne Klibanski, MD

President & CEO, Mass General Brigham

John Lechleiter, PhD

Chairman, Eli Lilly and Company

Gillian Leng, MD

Deputy Chief Executive, National Institute for Health and Care Excellence

John Lepore, MD

SVP, Head of Research, GSK

Min Li, PhD

SVP, Global Head of Neurosciences, GlaxoSmithKline

Husseini Manji, MD

Global Therapeutic Head, Neuroscience, Janssen Research & Development

David Mayhew, CBE

UK Dementia Envoy; Chairman, Alzheimer’s Research UK

Bob Oliver

CEO, Otsuka America Pharmaceutical

Peter Orszag, PhD

Vice Chairman, Corporate and Investment Banking, Citigroup

Steven Paul, MD

CEO, Voyager Therapeutics

Hugh Perry, PhD

Professor of Experimental Neuropathology, University of Southampton

David Roblin, MD

COO and Director of Scientific Translation, The Francis Crick Institute

Richard Rudick, MD

VP Development Sciences, Biogen

Martin Samuels, MD

Chair, Department of Neurology, BWH; – Miriam Sydney Joseph Professor of Neurology, HMS

Alfred Sandrock, MD, PhD

EVP, R&D and CMO, Biogen

Dennis Selkoe, MD

Co-Director, Ann Romney Center for Neurologic Diseases, BWH; – Vincent and Stellla Coates Professor of Neurologic Diseases, HMS

Rudolph Tanzi, PhD

Vice-Chair, Neurology, Director, Genetics and Aging Research Unit, MGH; – Joseph P. and Rose F. Kennedy Professor of Neurology, HMS

Howard Weiner, MD

Director, Multiple Sclerosis Program, BWH; – Robert L. Kroc Professor of Neurology, HMS

Day One: Monday, March 27, 2017

Disease Modifying Therapies: Getting over the Technology Threshold

  • Moderator: Jean-François Formela, MD, Partner, Atlas Venture
  • Kate Bingham, Managing Partner, SVLS
  • Min Li, PhD, SVP, Global Head of Neurosciences, GlaxoSmithKline
  • Vivek Ramaswamy, CEO, Roivant Sciences
  • Alfred Sandrock, MD, PhD, EVP, Chief Medical Officer, Head, Development and Worldwide Medical, Biogen
  • Dennis Selkoe, MD, Co-Director, Ann Romney Center for Neurologic Diseases, Brigham and Women’s Hospital; Vincent and Stella Coates Professor of Neurologic Diseases, Harvard Medical School
Watch Panel Here

Expanding the Diagnostic Spectrum: Tools, Technologies, and Tracers

  • Moderator: Bruce Rosen, MD, PhD, Director, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital
  • Roger Gunn, PhD, CSO, Imanova; Professor of Molecular Neuroimaging, Department of Medicine, Imperial College, London
  • Jacob Hooker, PhD, Phyllis and Jerome Lyle Rappaport MGH Research Scholar, Director of Radiochemistry, Athinoula A. Martinos Center, Massachusetts General Hospital; Associate Professor in Radiology, Harvard Medical School
  • Robert Krieg, PhD, VP of MR Product Definition & Innovation, Siemens
  • Eddie Martucci, PhD, CEO, Akili Interactive Labs
  • Henrik Zetterberg, MD, PhD, Professor of Neurochemistry, Head of Lab, UCL; Professor of Neurochemistry, Head of Department, University of Gothenburg
Watch Panel Here

1:1 Fireside Chat – John Lechleiter

  • Moderator: Hilary Evans, CEO, Alzheimer’s Research UK
  • John Lechleiter, PhD, Chairman, Eli Lilly and Company
Watch Panel Here

Patient Interview

  • Moderator: Martin Samuels, MD, Chair, Department of Neurology, Brigham and Women’s Hospital; Miriam Sydney Joseph Professor of Neurology, Harvard Medical School
  • Brenda and Stephen Whittle, PhD, Dementia Patient & Caregiver, Dementia Advocates and Volunteer Partners with ARUK (Alzheimer’s Research UK)
Watch Panel Here

Neurodegeneration and Neuroinflammation: A Grand Unifying Theory for Drug Development?

  • Moderator: Rudolph Tanzi, PhD, Vice-Chair of Neurology, Director of Genetics and Aging Research Unit, Massachusetts General Hospital; Joseph P. and Rose F. Kennedy Professor of Neurology, Harvard Medical School
  • Christian Haass, PhD, Institute Head, German Center for Neurodegenerative Disease
  • Michael Hayden, MD, PhD, President of Global R&D, CSO, Teva Pharmaceutical Industries
  • Michael Hutton, PhD, CSO, Neuroscience, Eli Lilly and Company
  • Roger Nitsch, MD, President, Neurimmune Holding AG
  • Hugh Perry, PhD, Professor of Experimental Neuropathology, University of Southampton
Watch Panel Here

Lunch Breakout: Depression and Neuroinflammation

  • Moderator: Philip Iredale, PhD, VP Head of Circuits, Neuro-Opportunities & Screening, Technologies, Pfizer
  • Declan Jones, PhD, VP, Neuroscience Lead, J&J London Innovation Centre, Johnson & Johnson
  • Kerry Ressler, MD, PhD, CSO, McLean Hospital; Professor in Psychiatry, Harvard Medical School
Watch Panel Here

The Promise and Current Role of Gene and Cell Therapy

  • Moderator: Ole Isacson, MD, PhD, Principal Investigator Harvard Stem Cell Institute, McLean Hospital; Professor of Neurology and Neuroscience, Harvard Medical School
  • Timothy Cox, MD, Professor of Medicine Emeritus, Director of Research, Honorary Consultant Physician, University of Cambridge
  • Brad Hyman, MD, PhD, Director, Massachusetts Alzheimer’s Disease Research Center, Massachusetts General Hospital; John B. Penney Professor of Neurology, Harvard Medical School
  • Gillian Leng, MD, Deputy Chief Executive, National Institute for Health and Care Excellence
  • Steven Paul, MD, CEO, Voyager Therapeutics
Watch Panel Here

Next-Generation Therapies and Diagnostics: Big Data and Digital Health

  • Moderator: Shawn Murphy, MD, PhD, Corporate Director of Research Information Systems and Computing, Partners HealthCare; Associate Professor of Neurology, Harvard Medical School
  • Jenny Barnett, PhD, CSO, Cambridge Cognition
  • John Gallacher, PhD Director, MRC Dementias Platform UK
  • Husseini Manji, MD, Global Therapeutic Area Head, Neuroscience, Janssen R&D
  • Richard Rudick, MD, VP Development Sciences, Biogen
  • Howard Weiner, MD, Director, Multiple Sclerosis Program, Brigham and Women’s Hospital; Robert L. Kroc Professor of Neurology, Harvard Medical School
Watch Panel Here

1:1 Fireside – Alfred Sandrock

  • Moderator: Rudolph Tanzi, PhD, Vice-Chair of Neurology, Director of Genetics and Aging Research Unit, Massachusetts General Hospital; Joseph P. and Rose F. Kennedy Professor of Neurology, Harvard Medical School
  • Alfred Sandrock, MD, PhD, EVP, Chief Medical Officer, Head, Development and Worldwide Medical, Biogen
Watch Panel Here

Implementing Novel Models in Alzheimer’s Trials: How Can We Transform the Cost-Benefit Equation for Trials?

  • Moderator: Reisa Sperling, MD, Director, Center for Alzheimer’s Research and Treatment, Brigham and Women’s Hospital; Professor of Neurology, Harvard Medical School
  • Iain Chessell, PhD, VP Neuroscience IMED MedImmune, AstraZeneca
  • Michael Krams, MD, Global Head of Quantitative Sciences, Janssen Pharmaceuticals
  • Craig Ritchie, MD, PhD, Professor of Psychiatry of Ageing University of Edinburgh
  • Nadeem Sarwar, MD, PhD, President, AiM Institute, Eisai
Watch Panel Here

The Crisis We Want: Are Healthcare Systems Prepared for a Disease-Modifying Drug?

  • Moderator: Merit Cudkowicz, MD, Chair, Department of Neurology, Massachusetts General Hospital; Julieanne Dorn Professor of Neurology, Harvard Medical School
  • Phyllis Ferrell, VP, Global Alzheimer’s Disease Platform Team, Eli Lilly and Company
  • Tim Ferris, MD, Senior Vice President of Population HealthCare Management, Partners HealthCare; Associate Professor of Medicine and Pediatrics, Harvard Medical School
  • Geoff Huggins Director of Health Social Care and Integration, Scottish Government
  • Bob Oliver, CEO, Otsuka America Pharmaceutical
Watch Panel Here

Announcement and Discussion of the Springboard Challenge

  • Moderator: Christopher Coburn, Chief Innovation Officer, Partners HealthCare
  • John Lepore, MD, SVP, R&D Pipeline GlaxoSmithKline
Watch Panel Here

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