After receiving his MD from Boston University, Dr. Arnold completed residency training in Psychiatry at the New York State Psychiatric Institute / Columbia Presbyterian Medical Center in New York, residency training in Neurology and fellowship training in Behavioral Neurology at the University of Iowa Hospitals and Clinics in Iowa City. Dr. Arnold is board certified in both neurology and psychiatry. 

At the Massachusetts General Hospital, Dr. Arnold leads the Alzheimer’s Clinical and Translational Research Unit, conducting early phase clinical trial and biomarker research.  He is also Managing Director of the Interdisciplinary Brain Center, a new collaboration of the Departments of Neurology, Psychiatry and Radiology. Its mission is to facilitate the discovery, development, and implementation of promising therapeutics and associated diagnostics for individuals with complex brain disorders affecting cognition, behavior and emotion. 

 Dr. Arnold has conducted longstanding research on neurodegenerative disease pathology, molecular biomarkers and therapeutics for cognitive decline and psychiatric syndromes in late life and has led broad clinical and translational research programs. He has authored over 350 scientific articles, reviews and chapters. Current scientific interests include biomarkers in brain aging and dementias, metabolic factors driving dementia, and protective factors that account for cognitive resilience, all with the goal of accelerating therapeutics discovery and development.