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2024 Event Site

First Look

At the 2024 World Medical Innovation Forum, 14 Harvard-affiliated Mass General Brigham clinicians and researchers shared 8-minute presentations highlighting their discoveries and insights on the next wave of breakthroughs in healthcare. With topics ranging from targeting neuroinflammation in Alzheimer’s Disease and counteracting age-related cognitive decline, to the promise of immunotherapy for brain cancer and safe AI, experts shared previews of investment-ready, high-impact technologies likely to disrupt healthcare in the coming months and years.

These showcased technologies are designed to inform investors, entrepreneurs, investigators, donors and others who share a passion for accelerating the application of high impact technologies to the benefit of patients.

2024 Winners

The World Forum’s First Look sessions promote early-stage innovations from across Mass General Brigham. Two of these presentations were selected with additional recognition for addressing unmet need, having clinical impact, scientific strength, and collaboration opportunities. In 2024 the two First Look prizes were awarded to John Hanna, MD, PhD, of Brigham and Women’s Hospital and Leigh Hochberg, MD, PhD, of Massachusetts General Hospital.

First-in-Class Proteasome Inhibitors for Multiple Myeloma and Other Cancers

John Hanna, MD, PhD

Associate Professor, Brigham and Women’s Hospital & Harvard Medical School

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Implantable Brain-Computer Interface for Restoring Communication and Mobility

Leigh Hochberg, MD, PhD

Director of Neurotechnology and Neurorecovery, Massachusetts General Hospital; Senior Lecturer on Neurology, Harvard Medical School

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2024 Presenters

Microneedle Drug Delivery Patch to Treat Autoimmune Skin Disease

Natalie Artzi, PhD

Associate Professor of Medicine, Brigham and Women’s Hospital & Harvard Medical School

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“Snake” Robotic Bronchoscope: Improving Maneuverability to Diagnose & Treat Hard-to-Reach Lung Cancers

Yolonda Colson, MD, PhD | Nobuhiko Hata, PhD

Chief, Thoracic Surgery Division, Massachusetts General Hospital; Professor of Surgery, Harvard Medical School | Director, Surgical Navigation and Robotics Laboratory, Brigham and Women’s Hospital; Professor of Radiology, Harvard Medical School

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First-in-Class Proteasome Inhibitors for Multiple Myeloma and Other Cancers

John Hanna, MD, PhD

Associate Professor, Brigham and Women’s Hospital & Harvard Medical School

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Implantable Brain-Computer Interface for Restoring Communication and Mobility

Leigh Hochberg, MD, PhD

Director of Neurotechnology and Neurorecovery, Massachusetts General Hospital; Senior Lecturer on Neurology, Harvard Medical School

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Enhancing Mental Health using Virtual Reality

Daphne Holt, MD, PhD

Director of the Resilience and Prevention Program, Massachusetts General Hospital; Associate Professor of Psychiatry, Harvard Medical School

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New Treatments for Lipid Abnormalities in the Brain

Ole Isacson, MD-PhD

Founding Director, Neuroregeneration Research Institute, McLean Hospital; Professor of Neuroscience and Neurology, Harvard Medical School

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Reimagining Precision Oncology Through Deep Learning-Enabled Computational Pathology Tools

Albert Kim, MD

Assistant Physician, Mass General Cancer Center; Assistant Professor, Harvard Medical School

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Automating Drug Administration: AI-powered Blood Pressure Management during Cesarean Delivery

Vesela Kovacheva, MD, PhD

Director of Translational and Clinical Research in Obstetric Anesthesiology, Mass General Brigham; Assistant Professor, Harvard Medical School

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Allogeneic Naïve B Cells as a Novel Cell Therapy Candidate for Regenerative Medicine

Marc Poznansky, MD, PhD | Ruxandra Sîrbulescu, PhD

Director, Vaccine and Immunotherapy Center, Massachusetts General Hospital; Steve and Deborah Gorlin MGH Research Scholar; Professor of Medicine, Harvard Medical School | Regenerative Medicine Program Director, Vaccine & Immunotherapy Center, MGH; Assistant Professor of Neurology, HMS

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RheumApp: Integrating Patient- Reported Outcomes into Routine Care

Daniel Solomon, MD

Matthew H. Liang Distinguished Chair in Arthritis and Population Health, Brigham and Women’s Hospital; Professor of Medicine, Harvard Medical School

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AI to Streamline Cardiovascular Clinical Trials

Scott Solomon, MD

Director, Clinical Trials Outcomes Center, Edward D. Frohlich Distinguished Chair in Cardiovascular Pathophysiology, Brigham and Women’s Hospital; Professor of Medicine, Harvard Medical School

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Multimodal, Minimally Invasive Imaging for Early Disease Detection

Guillermo Tearney, MD, PhD | Farouc A. Jaffer, MD, PhD

Principal Investigator, Wellman Center for Photomedicine, Massachusetts General Hospital; Remondi Family Endowed MGH Research Institute Chair; Professor of Pathology, Harvard Medical School | Director, Coronary Intervention, Mass General Cardiology; Director, MGH Chronic Total Occlusion (CTO) Percutaneous Coronary Intervention (PCI) program; Associate Professor of Medicine, Harvard Medical School

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Immersive, Mixed Reality Medical Education Platform

Raul Uppot, MD

Interventional Radiologist, Massachusetts General Hospital; Associate Professor, Harvard Medical School

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Non-Invasive Diagnosis of Sepsis in Neonates Using Saliva

David Walt, PhD

Professor of Pathology, Brigham and Women’s Hospital; Hansjörg Wyss Professor of Biologically Inspired Engineering, Harvard Medical School

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