Tanya Mayadas-Norton
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Tanya Mayadas, PhD

  • Professor, Pathology, BH
  • Professor, Pathology, HMS

Tanya Mayadas, PhD is a Professor of Pathology at Harvard Medical School and Staff Scientist at Brigham and Women’s Hospital. She received her PhD in Biochemistry from the University of Rochester, Rochester NY in 1990 and completed a joint post-doctoral fellowship at Tufts Medical Center and Massachusetts Institutes of Technology, Boston MA in 1993. She is internationally recognized for her work in immune and vascular cell mediated mechanisms of inflammation. She has established human neutrophil FcγRs (receptors for IgG) and the integrin, Mac-1 (CD11b/CD18) as primary mediators of neutrophil recruitment and associated organ damage in IgG-mediated autoimmune diseases that affect the kidney and delineated the signaling pathways that regulate these processes. These studies were facilitated by novel knock-out and FcγR humanized transgenic animals she developed. She has also made seminal discoveries about the role of renal TNF receptor 2 and downstream autocrine IFNβ signaling in glomerular inflammation and damage.

Her work also has a strong vascular biology focus. She studies cAMP dependent mechanisms regulating endothelial cell junction remodeling in the context of vascular permeability, which has implications for many inflammatory diseases. Her work has been continuously funded by NIH since 1994. Her scientific contributions have been recognized by a Young Investigator award by the Society of Leukocyte Biology (1996), an American Heart Association Established Investigator Grant (2001), the Stewart-Niewiarowski Award for Women in Vascular Biology (2010) and the Distinguished Innovator Award from the Lupus Research Institute (2015).

Covid-19 Broadcast
May 11, 2020
Live Event
May 10–12, 2021