At Brigham and Women’s Hospital (BWH), Dr. Masanori Aikawa is the Yoshihiro Miwa Associate Chair and Founding Director of the Center for Interdisciplinary Cardiovascular Sciences (CICS) and is Associate Professor of Medicine at Harvard Medical School (HMS). In 2009, he launched CICS in collaboration with the Japanese pharmaceutical company Kowa to establish a new model of academia-industry partnership in drug discovery research. CICS, where BWH and Kowa scientists work together in a shared space, also promotes business exchange between US and Japan. In his pre-existing laboratory, Dr. Aikawa has explored the role of Dll4-Notch signaling in cardiometabolic inflammation. He uses cutting-edge technologies, including global and targeted proteomics, single cell analysis, network analysis, and unique animal models.
Dr. Aikawa received his MD and PhD degrees from Juntendo University in Tokyo. Trained as a clinician in internal medicine and cardiology, his career goal is to translate basic research findings into clinical practice. His initial research at the University of Tokyo demonstrated the diversity of smooth muscle cell phenotypes in human arteries through the cloning and characterization of myosin heavy chain isoforms. Since 1995, his studies have focused on the role of inflammation in vascular disease at BWH/HMS.
Dr. Aikawa’s work has received worldwide recognition and led to numerous lectureship invitations and awards such as the American Heart Association Special Recognition Award in Vascular Biology. He has held editorial positions for major journals, including Circulation, Circulation Research, and Arteriosclerosis Thrombosis and Vascular Biology, and is a co-chief editor of Frontiers in Cardiovascular Medicine.