Dr. Kaplan is director of the Obesity, Metabolism and Nutrition Institute at Massachusetts General Hospital (MGH), founding Director of the MGH Weight Center and associate professor of medicine at Harvard Medical School (HMS), Boston, Massachusetts.
His research is focused on the physiological and molecular mechanisms of gastrointestinal regulation of energy balance and metabolic function, and he has pioneered the development and use of rodent models of bariatric surgery and gastrointestinal devices to explore these mechanisms. His group has recently demonstrated important contributions of central melanocortin-dependent circuits, brown fat thermogenesis, altered bile acid metabolism, the gut microbiota, and circadian regulation to these GI regulatory pathways.
Dr. Kaplan is director of the Blackburn Course in Obesity Medicine, director of the Obesity Medicine and Nutrition subspecialty fellowship program at Harvard and MGH and Associate Director of the NIH-funded Nutrition and Obesity Research Center at Harvard. He serves on the Advisory Council of the National Institute of Diabetes, Digestive and Kidney Diseases, the NIH Clinical Obesity Research Panel, and scientific advisory committees for several foundations, corporations and government research programs. He is Chair Emeritus of the Campaign to End Obesity.
Dr. Kaplan graduated from Harvard University and received his medical degree and doctoral degree in molecular biology from the Albert Einstein College of Medicine in New York, all with distinction. He completed an internship and residency in internal medicine and a fellowship in gastroenterology and hepatology at MGH and a fellowship in genetics at the Brigham and Women’s Hospital.
The author of more than 200 peer-reviewed papers, Dr. Kaplan has published in leading journals including the New England Journal of Medicine, Nature, Nature Genetics, Science, Gastroenterology, Cell Host and Microbe, the American Journal of Human Genetics and the Proceedings of the National Academy of Sciences of the USA.