Daniel M. Bloomfield MD, MPhil, FACC, FAHA is Senior Vice President, Global Clinical Development at Merck Research Laboratories, and is the Therapeutic Area Head for Cardiometabolic and Women’s Health Programs. In this role he currently leads a team responsible for a number of major programs including Januvia (sitagliptin), Zetia/Vytorin (ezetimibe), ertugliflozin (SGLT2 inhibitor – collaboration with Pfizer), anacetrapib (CETP inhibitor), a number of Women’s Health Programs in contraception and fertility, as well as programs in collaboration with Bayer AG focused on soluble guanylate cyclase activators Adempas (riociguat) approved to treat pulmonary hypertension and vericiguat being studied in patients with congestive heart failure. In addition to leading this therapeutic area, Dr. Bloomfield is responsible for the central coordination and strategic oversight of Merck’s R&D organization in China across all therapeutic areas.
Dr. Bloomfield joined Merck Research Laboratories in 2003 and to date has enjoyed a diverse career that has included discovery, as well as early and late clinical development. In 2011, he was chosen to chair the Early Development Research Committee which governs all programs in early development, was appointed Head of Global Project Management, and subsequently spent one year on assignment as Chief of Staff to the CEO Kenneth C. Frazier.
In addition to his executive duties, Dr. Bloomfield created the first Cardiac Organ Specific Safety Board at Merck, and was a founding member and co-chair of the Cardiac Safety Research Consortium (a public private partnership with the FDA, academia and industry) an organization devoted to advancing scientific knowledge on cardiac safety for new and existing medical products by building a collaborative environment based upon the principles of the FDA’s Critical Path Initiative, as well as other public health priorities. Dr. Bloomfield has also served as Rapporteur for the ICH E14 implementation working group.
After finishing a BA in Chemistry at Haverford College, Dr. Bloomfield took a Master’s degree in Social Anthropology at the University of Oxford as a Rhodes Scholar. Upon his return to the US, he attended Harvard Medical School and subsequently did his Internal Medicine and Cardiology training at Columbia before joining the faculty upon graduation.
As an Associate Professor of Medicine in the Division of Cardiology, his academic research was supported by grants from the NIH (K08, R01, K24), multiple foundations, and industry. He became recognized internationally as an expert in syncope (fainting spells), as well as novel methods used to identify patients at risk for sudden cardiac death. In addition to his work as part of the Columbia Clinical Trials Unit, Dr. Bloomfield’s clinical laboratory was also involved in studies related to T wave alternans, the autonomic modulation of cardiac repolarization as well as characterizing U wave behavior in diverse autonomic states.
Dan has created and been involved in a number of charitable organizations. In 1986 he created the American-South African Scholarship Association which provides university scholarships for disadvantaged students in South Africa, and went on to become the Founding President of the Friends of Mandela Rhodes Foundation (USA). Dan was also a Founding Member of the Board for SEED Impact, an organization that provides a catalyst for high performance and sustainability in not-for-profit organizations. Additionally, Dan is a Board Member of the New Jersey Center for Performing Arts, serves on its Executive Committee, and Chairs the Arts Education Committee.