Market Interest in Oncolytic Viruses | Calibrating - 2021 World Medical Innovation Forum
May 2–4, 2022

Market Interest in Oncolytic Viruses | Calibrating

Market Interest in Oncolytic Viruses | Calibrating

Wednesday, May 19, 2021

1:45 PM – 2:10 PM

There are currently two oncolytic virus products on the market, one in the USA and one in China.  As of late 2020, there were 86 clinical trials 60 of which were in phase I with just 2 in Phase III the rest in Phase I/II or Phase II.   Although global sales of OVs are still in the ramp-up phase, some projections forecast OVs will be a $700 million market by 2026. This panel will address some of the major questions in this area:

What regulatory challenges will keep OVs from realizing their potential? Despite the promise of OVs for treating cancer only one has been approved in the US. Why has this been the case? Reasons such have viral tropism, viral species selection and delivery challenges have all been cited. However, these are also true of other modalities. Why then have oncolytic virus approaches not advanced faster and what are the primary challenges to be overcome?

  • Will these need to be combined with other agents to realize their full efficacy and how will that impact the market?
  • Why are these companies pursuing OVs while several others are taking a pass?
Martine Lamfers, PhD
  • Visiting Scientist, BWH
  • Associate Professor, Erasmus Medical Center Rotterdam
Robert Martuza, MD
  • Consultant in Neurosurgery, MGH
  • William and Elizabeth Sweet Distinguished Professor of Neurosurgery, HMS
Jeffrey Infante, MD
  • Vice President, Early Development Oncology, Janssen
Anlong Li, MD, PhD
  • Clinical Director, Oncology Clinical Development, Merck Research Laboratories
Loic Vincent, PhD
  • Head of Oncology Drug Discovery Unit, Takeda
  • Q&A

    02:15 PM – 02:30 PM

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