CAR-T | Solid Tumors Success | When?
Wednesday, May 19, 2021
3:30 PM – 3:55 PM
Hot Topics
The potential application of CAR-T in solid tumors will be a game-changer if it occurs. The panel explores the prospects of solid tumor success and what the barriers have been. Questions include:
- How would industry and investor strategy for CAR-T and solid tumors be characterized? Has it changed in the last couple of years?
- Does the lack of tumor antigen specificity in solid tumors mean that lessons from liquid tumor CAR-T constructs will not translate well and we have to start over?
- Whether due to antigen heterogeneity, a hostile tumor micro-environment, or other factors are some specific solid tumors more attractive opportunities than others for CAR-T therapy development?
- Given the many challenges that CAR-T faces in solid tumors, does the use of combination therapies from the start, for example, to mitigate TME effects, offer a more compelling opportunity.
- Moderator:
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- Oladapo Yeku, MD, PhD
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- Clinical Assistant in Medicine, MGH
- Speakers:
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- Jennifer Brogdon
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- Executive Director, Head of Cell Therapy Research, Exploratory Immuno-Oncology, NIBR
- Knut Niss, PhD
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- CTO, Mustang Bio
- Barbra Sasu, PhD
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- CSO, Allogene
- Jay Short, PhD
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- Chairman, CEO, Cofounder, BioAlta, Inc.
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Q&A
04:00 PM – 04:15 PM