AAV Delivery - 2021 World Medical Innovation Forum
May 2–4, 2022

AAV Delivery

AAV Delivery

Wednesday, May 19, 2021

11:20 AM – 11:45 AM
Hot Topics

This panel will address the advances in the area of AAV gene therapy delivery looking out the next five years. Questions that loom large are: How can biodistribution of AAV be improved? What solutions are in the wings to address immunogenicity of AAV? Will patients be able to receive systemic redosing of AAV-based gene therapies in the future? What technical advances are there for payload size? Will the cost of manufacturing ever become affordable for ultra-rare conditions? Will non-viral delivery completely supplant viral delivery within the next five years?What are the safety concerns and how will they be addressed?

Xandra Breakefield, PhD
  • Geneticist, MGH, MGH
  • Professor, Neurology, HMS
Florian Eichler, MD
  • Director, Center for Rare Neurological Diseases, MGH
  • Associate Professor, Neurology, HMS
Jennifer Farmer
  • CEO, Friedreich's Ataxia Research Alliance
Mathew Pletcher, PhD
  • SVP, Head of Gene Therapy Research and Technical Operations, Astellas
Manny Simons, PhD
  • CEO, Akouos
  • Q&A

    11:50 AM – 12:05 PM

the Future of Medicine and AI

May 11–13, 2020 | Boston, MA