Dr. Is In Sessions
Tuesday, May 3, 2022
Lunch Sponsored by Astellas
Understanding long-term Gene and Cell Therapy investment complexities requires a keen awareness of where the science and the markets are headed. That’s why “The Doctor is In” in these updates on the latest GCT technologies. Presented by Mass General Brigham clinicians and innovators from the front lines of care, the sessions are co-hosted by expert analysts from Bank of America and include interactive discussion and Q&A.
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Personalizing Cancer Care through RNA Therapies
11:45 AM – 12:45 PM View HereIn this session, Dr. Peruzzi will discuss how RNA for cancer therapy is a versatile of a tool for a protean problem.
- Moderator:
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- Jason Gerberry
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- Managing Director, Global Research, BofA Securities
- Panelist:
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- Pierpaolo Peruzzi, MD, PhD
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- Neurosurgeon and Principal Investigator, BWH
- Assistant Professor of Neurosurgery, HMS
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Designing for Success: Clinical Trial Approaches for Rare and Ultra-Rare Diseases
11:45 AM – 12:45 PM View HereIn this session, Dr. Vavvas will discuss examples of clinical trials in rare diseases and share insights into how clinical trials should be approached for rare and ultra-rare diseases and how study design is not a one-size fits all.
- Panelist:
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- Demetrios Vavvas, MD, PhD
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- Associate Director of the Retina Service, Mass Eye and Ear
- Solman and Libe Friedman Professor of Ophthalmology, Co-Director Ocular Regenerative Medical Institute, HMS
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A New Hope: Cell Therapy and Transplantation for Parkinson’s Disease
11:45 AM – 12:45 PM View HereIn this session, hear experts weigh in on the possibilities of cell therapy development and transplantation for the treatment of Parkinson’s Disease. What does the futures hold and how do we get there?
- Moderator:
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- Greg Harrison
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- Vice President, Global Research, BofA Securities
- Panelist:
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- Bob Carter, MD, PhD
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- Chairman, Department of Neurosurgery, MGH
- William and Elizabeth Sweet Professor of Neurosurgery, HMS
- Todd Herrington, MD, PhD
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- Director, Deep Brain Stimulation Program, MGH
- Assistant Professor of Neurology, HMS
- Kwang-Soo Kim, PhD
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- Director, Molecular Neurobiology Laboratory, McLean
- Professor of Neuroscience and Psychiatry, HMS
- Jeffrey Schweitzer, MD, PhD
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- Neurosurgeon, MGH
- Assistant Professor of Neurosurgery, HMS
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The Inner Workings of Gene Therapy Manufacturing
11:45 AM – 12:45 PM View HereIn this session, Dr. Nikiforow will provide insights into the world of gene therapy manufacturing and the complexities of scaling, costs and insurance reimbursement.
- Moderator:
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- Michael Ryskin
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- Director, Global Research, BofA Securities
- Panelist:
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- Sarah Nikiforow, MD, PhD
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- Medical Director, Cell Manipulation Core Facility, Technical Director, Immune Effector Cell Therapy Program, DFCI
- Assistant Professor, HMS
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The Road Ahead: Regulatory Challenges for Gene and Cell Therapy
11:45 AM – 12:45 PM View HereIn this session, Dr. Marks will discuss the ins and outs of regulatory challenges for biological products and therapies in gene and cell therapy and the responsibility to assure safety and effectiveness.
- Moderator:
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- Geoff Meacham, PhD
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- Managing Director, Global Research, BofA Securities
- Panelist:
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- Peter Marks, MD, PhD
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- Director, Center for Biologics Evaluation and Research, FDA
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The Mysterious Dark Genome
11:45 AM – 12:45 PM View HereDark genome, accounting for ~98.5% of the human genome and containing the non-coding part, offers unprecedented opportunity to look for novel elements that could play a role in human health. This non-coding region consists of repeat elements, enhancers, regulatory sequences and non-coding RNAs. This session will explore this exciting new frontier in biology and how to translate this so called “junk” and previously ignored genome into potential novel therapeutics.
- Moderators:
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- Angela Shen, MD
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- Vice President, Strategic Innovation Leaders, Mass General Brigham Innovation
- Richard Young, PhD
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- Professor, Whitehead Institute, MIT
- Panelists:
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- Rosana Kapeller, MD, PhD
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- Co-Founder, President & CEO, ROME Therapeutics
- Josh Mandel-Brehm
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- President & CEO, CAMP4 Therapeutics
- Amir Nashat, PhD
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- Managing Partner, Polaris Ventures
- Issi Rozen
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- Venture Partner, GV